The disease incubation period, the average is 12 days after obtaining the virus, but this period can vary between 7-17 days.

At the beginning of the disease and finding common complaints of high fever, weakness, headache and back pain. Typically occur in patients with red rashes: Spills are most face, arms and legs exposed. Rash flat (not detached) and usually begins as red spots all at the same time all starts. In the second week of this straight-red spots inside Puy (pus) and stuffed shells and begin to mount. Three or four weeks at the end of the shell debris bonds, leaves and begins to fall. Although most patients completely improved, 30% as the disease can result in death.

Transition of the disease from person to person, infected people with viral particles containing saliva is. In people with smallpox in the first week of infectious diseases is highest: in the first week because the virus has tükrükte lot. Poured from the middle but completely infectious waste can continue to shield.

Implemented routine vaccination programs against errors flowers in 1972 ended. 1972 or in 1972 before the smallpox vaccine made of people currently in the disease resistance (immune whether they) are not known exactly which is uncertain. Therefore, the moment everyone is assumed to be sensitive to smallpox.