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Chemotherapy, at least possible damage to normal cells, the drug can kill cancer cells is a method of treatment. Chemotherapy prevents cancer cells from multiplying. The first is a method of treatment for cancer chemotherapy sometimes. However, chemotherapy is usually applied after other treatments. Chemotherapy is not affected by surgery or radiotherapy treatment would assist in killing cancer cells.
Some people must be treated in the hospital. Some people, the chemotherapy treatment may come to the hospital for several hours. In some cases treatment may be applied at home. Chemotherapy usually two or three-week intervals, each session will be applied a few days to a few hours. Treatment for several months, a period of time usually applies. Chemotherapy is usually applied with a needle from the vein. Some people, regular intravenous chemotherapy in order to assist in implementing a tube is inserted under the skin. This process prevents the vessels to be too much damage. Tubes, treatment remains under the skin until it ends. Chemotherapy also in tablets, injections to the muscles through the skin can be applied over the cream.
Chemotherapy can cause temporary side effects. With vomiting and nausea may cause loss of hair and body hair. Nausea and vomiting may be useful in eliminating drugs. Hair and body hair during chemotherapy treatment of deciduous finished a few months after the re-start to get out. Chemotherapy also can cause long-term side effects. In this context, can affect a person’s fertility. For example, for a period or menstruation may stop completely. plans to have children, but you need to see if chemotherapy, ask a doctor what you can do about it. For example, men’s sperm can be stored in a clinic or hospital.
Questions to ask your doctor about chemotherapy:
• How long will the treatment?
• What are the possible side effects of treatment?
• No long-term side effects of treatment have a?
• To look at myself during Chemotherapy What can I do?
• During Chemotherapy and / or after treatment for immunological Tonic SLS I use XP?
Chemotherapy Drugs
Chemotherapy Treatment & Side Effects:
Listed below in the case and possible side effects of chemotherapy drugs are presented. The important point to keep in mind for each drug, these side effects can be seen, certain proportions or no side effects in some patients the emerging.
BCNU (Carmustine): Application to the inner vessel varies between 15 to 45 minutes. Shorter infüzyonlarda; vessels can be seen in the severe burning and swelling. Among the side effects of bone marrow suppression, these side effects are seen and usually occurs later. Other side effects, burning and pain along the vein is applied, the percentage flushing, nausea and vomiting. Among the rare side effects, often reversible liver and kidney function deterioration is seen. Long-term treatment was applied if the lung damage (toxicity) can cause to occur (shortness of breath are creating), and in this case may create a risk of death.
Bleomycin: Application intravenous, intramuscular, subcutaneous or intrakavital (lung membrane, into the peritoneum) is changed. Among the side effects of fever and severe skin reactions (played to black discoloration of the skin) as well as burning and inflammation of the skin, swelling and thickening is seen in the nail slot. Hair loss, itching and headache are among the side effects can be seen. 400U from reaching a higher total dose in the case of high-risk lung toxicity was observed.
Busulfan: Oral uygulanmaktadır.Yan effect as low dose applied low leukocyte count, the high dose pansitopenidir applied. In the lungs that leads to shortness of breath can cause fibroza but this is rarely fatal. Hormonal as gynecomastia (breast tissue growth), testicular damage or dysfunction, impotence and amenoreye (amonerrhea) olabilmektedir.Böbrek higher cause deterioration of gland function and skin are among the side effects common nigrescence.
Carboplatin (Paraplatin) in Vascular implemented. Side effects, particularly bone marrow suppression and increase the risk of bleeding with thrombocytopenia. These, as well as nausea, vomiting, and nephrotoxicity (kidney damage), neurotoxicity (in feet numbness and tingling in hands) and ototoxicity (hearing decrease in sensory) side effects that can be seen between them sisplatine Although relatively less. Rare side effects, the (less than 3%) hair loss, skin rash, scarring in the mouth and a cold case is similar (fever, chills, chills, headache, joint pain, muscle pain).
CCNU (Lomustin) is implemented through the mouth. Should be taken on an empty stomach. Dose limiting side effects, increasing the risk of infection, bone marrow suppression, bleeding and anemia are. Among other side effects, diarrhea, appetite loss, numbness, coordination disorder are included. Hair loss and temporary deficiency in liver function are among the side effects that may occur.
Chlorambucil (leukeran) is being implemented through the mouth. Erythrocytes of blood cells, leukocytes and platelets, leading to decreased bone marrow suppression is the dose limiting side effects. Applied in high doses, central nervous system, such as effects on the seizure and coma were observed. Although not very frequent stomach aches and bowel contractions may occur in the system. When used as a long-term treatment may be due to the formation of lung damage. Finally, this agent being used sperm formation can be pressure.
Cholrodeoxyadenosine (Cladribine): Application of continuous intravenous infusion ranged from 5 to 7 days. The main side effect of the decline is seen in neutrophil and lymphocyte cells. This decline occurred while bacterial infections to occur, due to drug suppression of the immune system can cause dangerous infections to occur. 50% of patients using this drug in the skin redness and rash formation was seen.
Cis-platinum: vein or body cavity through the patient’s fluid balance uygulanmaktadır.İlacı to use must be good. Fluid balance is insufficient in the event of side effects more severe than the emergence of kanıtlanmıştır.Böbrek function with inadequate, hearing difficulties which previously neuropathy (peripheral nervous system damage) exposed or cis-platinum allergy in patients with applying extremely cautious should behave. Side effects of nausea, vomiting and anaphylactic reactions (rapid pulse, wheezing, fallen blood pressure and percentage consisting of edema), kidney function impairment, hearing difficulties, hand and feet tingling and numbness creates nerve damage, bleeding and infection causing bone marrow suppression, electrolytes (sodium, potassium, magnesium) imbalances and heart disease are.
Cytarabine (Ara-C): Application subcutaneous, intramuscular or intravenous as can be made. Dose limiting toxicity, usually of bone marrow suppression is to be emerging. High total dose applied to the permanent central nervous system damage may cause. Damage that may occur in the cerebellum, difficulty speaking, walking in the strain, visual impairment and the mechanism may lead to some neurological problems. Damages generally higher in the cerebellum in patients 50 years is emerging. Other side effects may occur, skin rash, nausea and vomiting, diarrhea, appetite loss, mouth sores that formed in the temporary liver dysfunction, fever, body ache, skin rash and can develop a cold, is like a table. Lung involvement may occur rarely in the liquid.
Cyclophosphamide (Endoksan) is being implemented through the mouth or veins inside. Side effects, bone marrow suppression, hemorrhagic cystitis (bloody urine in the bladder with severe burning sensation), hair loss, electrolyte imbalances (especially sodium), nausea and vomiting occur with gastrointestinal damage and liver dysfunction are rare. Visible damage to the lungs. As sexual; one skip, testicular and ovarian disorders may occur in the function. Infertility can do it.
Docetaxel (Taxotere): Application is made through blood vessels. Dose limiting side effects, neutropenia (low blood leukocyte count) and, rarely, low platelet (blood clotting cells that provide a reduction in the number) is the number. Allergic reactions, lung and may cause swelling in the legs. Tingling and numbness in hands and feet nerve damage that can create.
Doxorubicin (Adriamycin) used vessels is through general practices. Side effects, bone marrow suppression, stomatitis (mouth which wound), nausea, vomiting and diarrhea are rare. Skin hyperpigmentation (darkening of skin color) and color changes in nails, as well as can be seen in the eyes burning and excessive aging are among the possible side effects. Cause noticeable hair loss. Received radiotherapy in patients with mild skin reactions are seen renewed.
In the case of foreign vessels entering (Ekstravazasyon) leakage in the region may lead to deep tissue damage. Deep in the skin of the patients seen 33′ünde% Ekstravazasyon scarring was seen. The resulting wound may require surgical intervention, sometimes in good condition.
The most important side effect of doxorubicin application is the development of heart damage. Applied dose-dependent development of the medical treatment of heart damage is very difficult. The emergence of this complication to be effective in risk factors, the maximum dose of 550mg/m2 dose to reach a patient being 70 years old and over, heart area and have received radiotherapy in the past, heart attack or high blood pressure with heart disease, such as is.
Etoposide (VP-16, VePesid): Application by vessels at least 30 minutes shaped. If the drug was given too quickly severe hypotension (low blood pressure) may occur. Etoposide at the same time also can be given by mouth. Many of the drug outside the vessel should avoid. The main side effect is to bone marrow suppression. Nausea, vomiting and loss of appetite may occur. Other side effects, hair loss, headache, fever and low blood pressure is the. Rarely, heart attack, heart failure, nerve damage, fatigue, sleep, and hands-tingling in the feet may occur. In addition, leukemia (blood cancer) may have an increased risk of development was seen.
5-Flourouracil (5-FU) and some body cavity through the veins can be applied. Side effects, nausea, vomiting, wounds in the mouth (stomatitis-mucositis) formation, in the esophagus and stomach ulcers are sores. As can be seen low WBC count, hair loss and color changes in nails can occur. Becomes sensitive to the sun for skin from the sun avoidance is recommended. Headache, visual disturbances and loss of balance while walking (cerebellar ataxia) is the side effects such as rare side effects. Chest pain, irregular heartbeats and sudden death in the form of reported cases of heart damage is possible, but mechanisms are unknown. In addition, skin redness and swelling, hand-feet can cause a burning feeling.
Fludarabine (Fludara): Application by vascular short-term (around 30 minutes) or the mouth is through. Among the side effects are bone marrow suppression. This case, the risk of infection artırmaktadır.Diğer side effects of nausea, vomiting, diarrhea (30% of patients), mild and transient renal and liver failure. Sleep and skin rash are rare side effects. Inflammation of the lungs (interstitial pneumonia) is less but is recycled within a few weeks.
Gemcitabine (Gemzaar): Application by vessels is around 30 minutes. Side effects, which increase the risk of bleeding is to bone marrow suppression (decreased platelet count). Other side effects, skin rash, fever, nausea, vomiting and flu-like is the table.
Herceptin (Trastuzumab): Application is via veins. Common side effects had been given alone, diarrhea, chills, fever, headache, dizziness, low blood pressure and skin rash are. Side effects when given with chemotherapy for the heart is increased. When used in combination with other drugs are common side effects of mild and moderate in other upper respiratory tract infections.
Ifosfamide (Haloksan): Application to short-term through veins and around 30 minutes, although the long-term applications (up to 120 hours) are out. Support the use of high doses of mesna and fluid ifosfomid arising from the use hematüriyi (bloody urine) is required in order to prevent.
Hair loss, nausea, vomiting and bone marrow suppression are among the reported side effects. Neurological toxicity when used in high doses Ifosfamid may occur. Of seizures, difficulty in walking and weakness of such a complication was encountered.
Irinotecan (Campton): Application is via veins. Limiting side effects of diarrhea and low-dose is the number of leukocytes (increases the risk of infection). Other side effects, nausea, vomiting and hair loss. With fever and shortness of breath can be seen emerging pulmonary toxicity.
Melphelan (Alkeran): Application are made orally. Absorption is best done on an empty stomach. The main side effect is to bone marrow suppression. Used long-term myelodysplasia and leukemia (blood cancer) increases the risk. Other side effects, hair loss, stomatitis (sores in the mouth), dermatitis (ekzema) and lung fibrozisidir. Besides this, low blood pressure all basics severe allergic reactions, sweating and heart disease have been reported.
Methotrexate: oral, into muscle, blood vessels or into the intrathecal (into the region of the membranes surrounding the brain) can be applied. Bone marrow suppression (increases the risk of infection), nausea, vomiting, loss of appetite, common side etkileridir.Dişeti infection, arthralgia, mucosal ulcer formation are other side effects. Liver failure, skin rash, itching, color changes, hair loss and side effects such as sensitivity to light have been reported. When using high doses can cause kidney failure. Dizziness, turbidity, chills, fever, was also experience side effects such as pulmonary fibrosis.
Mitoxantrone (Novantrone): Application path is from vessels. Ekstravazasyona of the drug (the drug leaking out of vessels) should be very careful not to lead. Dose of bone marrow suppression side effect is to restrictive. Other side effects of nausea, vomiting and stomatittir (sores in the mouth). Among the rare side effects, constipation and hair loss are available.
For heart side effects may occur. To prevent this, the maximum dose applied (toplamdozun) 160mg/m2 ’should not exceed.
Oxaliplatin (Eloxatin): Vascular via short-term or extended up to 120 hours continuous infusion can be applied. Nerve damage (hand and feet numbness and tingling of the lips sometimes) may be correct, but usually after discontinuation of the drug. Leukocytes and platelets in the blood can cause slight decreases.
Paclitaxel (Taxol): Application is via veins. During drug application, allergic shock and other allergic reactions raslanabilmektedir. These reactions; wheeze, shortness of breath, facial flushing, swelling and decreased blood pressure (hypertension) is.
Taxol ‘reputation is to bone marrow suppression is the dose limiting side effects. Numbness, tingling and pain occur with neuropathy (nerve damage) are the side effects that can be seen. Use of the drug can cut back when neuropathy. It usually takes several months of complaints, but lost. To slow down the heart rate (bradycardia) causes, but this is short term. Other side effects, nausea, vomiting, diarrhea, mouth sores, hair loss, joint-muscle pain syndrome, including colds, fever, skin rash, headache and fatigue is.
Procarbazine (Natulan): Application by mouth or vein is from the path. Certain foods and drugs interact with Procarbazine’nin have. Therefore, these foods and drugs should not be taken during treatment. Some drugs can cause these side effects of ethanol (alcohol), ephedrine, epinefrindir. These drugs, nausea and vomiting, visual discomfort and headache as well, such as chest pain and heart disease also may cause abnormal heart rate. Beer, cheese, wine, food, like bananas with high blood pressure, tremors, excitation (increase in severe psychomotor activity) chest pain, abnormal heart rate can cause heart disease, such as layout. Bone marrow suppression is the dose limiting side effects (increases the risk of bleeding and infection). Other side effects, nausea, vomiting, fever, chills, sweating, joint and muscle pain, cold complaints that are created. Hair loss, itching and skin rash have been reported. Nervous system toxicity (side effect) dizziness, disturbances in walking, numbness and tingling hands and feet is. Sensitivity to light and infertility in women and men can do in one jump.
Maphthera (Rituximap) is applied through the veins. Side effects of fever, chills, nausea, vomiting, fatigue, itching, wheezing, shortness of breath, low blood pressure and swelling in the throat or in the language is. Pain and fever can be seen in the disease area.
Immunological as the majority of patients with B-lymphocytes in the blood cells was seen in the reduction, but this causes no increase in the risk of infection. Bone marrow suppression and anemia is rare. Irregular and / or fast pulse rate leading to karditoksisite (heart side effects) have been reported. Rarely, joint pain, diarrhea, high blood pressure, chest pain, appetite loss, internal distress, fatigue, and lack of taste can do.
Topotecan (Hycamtin): Application is via veins. The main side effects that increase the risk of neutropenic infection. Low platelets and anemia side effects are also reported. Nausea and vomiting was observed in 30% of patients. Patients 1 / 3 at the rate of fire has been observed and 10% higher than 40 degrees-at the microscopic level in 12 urine bleeding was encountered.
Vinblastine: Implementation of total dose given within 1 minute from the vessel-shaped. This drug has features for severe irritant to the skin at or should not be given into muscle.
The main side effect is to bone marrow suppression. These side effects blood leukocytes (white blood cells), is due to decline in the number of red blood cells and platelets. These decreases, increasing the risk of infection and bleeding, as the decrease in exercise tolerance and shortness of breath that is caused. Rarely, nausea, vomiting, constipation and abdominal pain are seen. Distress, headache, malaise, created in the jaw pains, urinary problems, and convulsions (involuntary contraction) emerged as the neurotoxicity (neuronal loss) are reported side effects. Other side effects, mild hair loss, scarring in the mouth and skin against the sun is growing sensitivity.
Vincristine (Oncovin): Application is via veins. Vincristine and sometimes severe pain, seizures, constipation and bladder dysfunction that leads to the nörotoksisiteye (damage to the nervous system) causes. Ekstravazasyondan (drug leaking out of vessels) should be avoided. limiting side effects in the doses nörotoksisitedir (neuronal damage).
Vinorelbine (Navelbine): Usually 20 to 30 minutes in the vicinity of vessels is applied. The main effect of bone marrow suppression is to yen. These side effects low leukocyte (white blood cells decrease in the blood), and anemia covers. Neurotoxicity (nervous system, consisting of unwanted side effects) in 30% of patients, constipation and hand-formed feet in the form of complaints such as numbness and tingling. ¼ of the patients at the rate of hair loss is seen.
During chemotherapy you will see yourself how
• Less frequent meals and eat. 5 to 6 times a day in the form of snack food will help digest your food. Fruit cocktail is a good choice for a meal.
• Do not eat after stretching. Digestive yourself and let your body around 1 hour. Try to make the short walk after dinner, if you need to rest your legs stretched and fit to support your head with pillows.
• Do not take liquids for dinner. In this way, full power to run your digestive fluid and accelerating the digestion fluid intake until you can get indigestion among azaltacaktır.Yemek. (At least 1 hour before or after meals). Vegetable and fruit juices and meat / chicken soup or water, try to drink. Stay away from sugar as much as possible if you want to eat sugary food, try the products obtained from cereals.
• Stay away from all food fat relaxing. Make sure your diet with fresh fruit, steamed or boiled vegetables, grains and light continue to eat your protein.
• If you are experiencing vomiting and severe diarrhea, try the vegetable soup. This diet will keep the balance of salt for the electrolyte to support yourself when you feel weak at times of imbalance will protect you and your body.
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